Matthew Lani garnered thousands of followers by sharing medical advice and selling medication online.
On Sunday night, Mr Lani tried to bypass security by disguising himself with a surgical mask and stethoscope.
He tried to escape police custody by jumping out of a bathroom window, before being caught.
Gauteng province’s Department of Health released a statement saying Mr Lani frequently used the Helen Joseph Hospital in Johannesburg where he was caught to “curate misleading content under the pretence that he was a qualified doctor”.
He had almost 300,000 followers on TikTok before his account was closed. He then opened another one, which has more than 50,000 followers.
His arrest follows a manhunt lasting several weeks after questions arose over his qualifications.
Mr Lani says he received a medical degree from the University of Witwatersrand in Johannesburg. The institution says this is not the case.
The Department of Education says Mr Lani did not even obtain his school-leaving certificate.
He allegedly tried to mislead authorities by saying his real name was Dr Sanele Zingelwa – a second-year medical intern at the Tembisa Provincial Tertiary Hospital.
Dr Zingelwe has opened a criminal case against Mr Lani, accusing him of fraud.
Mr Lani is only the latest person to be arrested on charges of impersonating a doctor in South Africa.
According to the Ministry of Health, there have been about 124 such arrests over the last three years.
Source: BBC NEWS
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