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Harsh flu season has health officials worried about brain complications in children

WASHINGTON (AP) — This year’s harsh flu season – the most intense in 15 years – has federal health officials trying to understand if it sparked an increase in a rare but life-threatening brain complication in children.

The Centers for Disease Control and Prevention estimates 19,000 people have died from the flu so far this winter, including 86 children. Thursday, the CDC reported at least nine of those children experienced brain complications, and it has asked state health departments to help investigate if there are more such cases.

There is some good news: The CDC also reported that this year’s flu shots do a pretty good job preventing hospitalization from the flu — among the 45% of Americans who got vaccinated. But it comes a day after the Trump administration added to the uncertainty roiling government health agencies by canceling a meeting of experts who are supposed to help choose the recipe for next winter’s flu vaccine.

Still, it’s not too late to get vaccinated this year: “If you haven’t gotten your flu shot yet, get it because we’re still seeing high flu circulation in most of the country,” said Dr. Sean O’Leary of the American Academy of Pediatrics.

Flu shot effectiveness varies from year to year. While not great at blocking infections, the vaccine’s main role “is to keep you out of the hospital and to keep you alive,” said Vanderbilt University vaccine expert Dr. William Schaffner.

Preliminary CDC data released Thursday found children who got this year’s vaccine were between 64% and 78% less likely to be hospitalized than their unvaccinated counterparts, and adults were 41% to 55% less likely to be hospitalized.

What about those brain complications? Earlier this month, state health departments and hospitals warned doctors to watch for child flu patients with seizures, hallucinations or other signs of “influenza-associated encephalopathy or encephalitis” — and a more severe subtype called “acute necrotizing encephalopathy.” Encephalitis is brain inflammation.

Thursday, the CDC released an analysis of 1,840 child flu deaths since 2010, finding 166 with those neurologic complications. Most were unvaccinated. But the agency concluded it’s unclear if this year’s nine deaths with those complications — four of whom had the worse subtype — mark an uptick.

There’s no regular tracking of those neurologic complications, making it hard to find the answers. In California, Dr. Keith Van Haren of Stanford Medicine Children’s Health said earlier this month that he’d learned of about 15 flu-related cases of that severe subtype from doctors around the country and “we are aware or more cases that may also meet the criteria.” He did not say how many died.

O’Leary, with the pediatricians’ academy, said parents should remember this complication is rare — the advice remains to seek medical advice anytime a child with flu has unusual or concerning symptoms, such as labored breathing.

Doctors see more neurologic complications during severe flu seasons – they may be linked to particular influenza strains — and survivors can have ongoing seizures or other lingering problems, he said.

Meanwhile, vaccine makers already are gearing up for the months-long process of brewing next winter’s flu shots. A Food and Drug Administration advisory committee was supposed to meet on March 13 to help choose which flu strains to include but with that meeting’s cancellation, it’s unclear if the government will decide on its own.

“We have historically worked really hard to get transparency around all of these vaccine discussions,” said O’Leary, who said it’s important for the public to understand what goes into making decisions about the flu vaccine composition and other vaccine recommendations.

“The FDA will make public its recommendations to manufacturers in time for updated vaccines to be available for the 2025-2026 influenza season,” Andrew Nixon, communications director for the Department of Health and Human Services, said in an email.

Source: AP

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There’s been a global trend in the reduction of aid to Africa since 2018. Donors are shifting their funding priorities in response to domestic and international agendas. Germany, France and Norway, for instance, have all reduced their aid to Africa in the past five years. And, in 2020, the UK government reduced its Overseas Development Aid from 0.7% of gross national income to 0.5%. Many health services across the African continent rely heavily on overseas aid to provide essential care. International funding supports everything from vaccines and HIV treatment to maternal health programmes. Cuts to aid, particularly unilateral ones, can have widespread implications. For instance, about 72 million people missed out on treatment for neglected tropical diseases between 2021 and 2022 due to UK aid cuts. The freeze of US aid to Africa in January 2025 is the latest in this trend. It’s already having significant and wide-ranging impacts across the African continent. For example, vaccination campaigns for polio eradication and HIV/Aids treatment through the President’s Emergency Plan for AIDS Relief (Pepfar) have been stopped. This puts millions of lives at risk. In South Africa alone, the cut of Pepfar’s US$400 million a year to HIV programmes risks patients defaulting on treatment, infection rates going up and eventually a rise in deaths. President Donald Trump’s actions have highlighted Africa’s reliance on foreign aid for health funding. I’m a global health expert who sits on various funding and advisory boards, including those of the World Health Organization (WHO), the UK government and boards of global resource mobilisation organisations. I am well aware of the competing funding priorities for international funders and have long advocated for local, sustainable health funding mechanisms. Long-term strategies to reduce aid dependency are critical. Breaking away from this current funding status requires concerted efforts building on proven best practice. Country-leadership and ownership African countries currently face the unique challenge of simultaneously dealing with high rates of communicable diseases, such as malaria and HIV/Aids, and rising levels of non-communicable diseases, such as cardiovascular diseases and diabetes. But Africa’s health systems are not sufficiently resourced. They’re not able to provide appropriate, accessible and affordable healthcare to address these challenges. African governments spend less than 10% of their GDP on health, amounting to capital expenditure of US$4.5 billion. This falls short of the estimated US$26 billion annual investment needed to meet evolving health needs. Aid goes towards filling this funding gap. For example, in 2021, half of sub-Saharan African countries relied on external financing, such as grants and loans, for more than one-third of their health expenditures. Foreign aid has helped. But it clearly leaves African countries vulnerable to the political mood swings among funders. It also leads to loss of self-determination in terms of health priorities as, ultimately, the funder determines the health priorities. This is one reason why many programmes in Africa focus on a single disease, such as HIV. This leads to poorly integrated health services. For instance health workers or services are channelled into managing a single disease. New, underutilised financing options The current trajectory of reduced aid to Africa is likely to continue. Global aid is being directed to other challenges, such as conflict and illegal immigration. The continent cannot continue on the same path while hoping for different outcomes. Africa needs to grow a range of immediately available domestic financing options. Many of these are underutilised and include: 1.) Diversifying domestic resource mobilisation. This should include commodity taxation to fund health. For instance, tobacco taxes which are currently underutilised in Africa. Zimbabwe offers a successful example. It has bridged donor resource gaps through its 3% Aids levy (started in 1999). Imposed on both individual and corporate incomes, it funds domestic HIV/Aids prevention, care and treatment programmes. Nigeria’s another country that’s taken initiative, prioritising domestic budget allocation to health. It recently absorbed the 28,000 healthworkers formerly paid by USAid. This demonstrates that domestic health financing in Africa is possible. 2.) More private-public partnerships. Formed between local and international philanthropies or institutions, these can bridge financing gaps. One successful example is the 2015 health service provision partnership between the Kenyan government and GE Healthcare. GE Healthcare provides radiography equipment and services which the government pays for over time. This allows the government to budget and plan healthcare expenditure over several years. 3.) Promotion of regional integration to boost local production. This will reduce the need for aid-funded imported medical products. For instance, the African Union’s harmonised Africa Medicines Authority registration facility creates a single continental market for medicines. This supports local producers and exporters, by allowing them to operate on a larger scale. It also makes production and distribution more cost-effective. Finally, it reduces the reliance on imported medicines, strengthening Africa’s pharmaceutical industry. 4.) Leverage development finance institutions. These are specialised financial organisations – such as the Africa Development Bank, African Export-Import Bank and the Development Bank of Southern Africa. They can provide capital and expertise to projects deemed too risky for traditional investors. This includes support for health financing for infrastructure development, private sector development for small and medium-sized enterprises and the regional integration. One transformative initiative is the AfricInvest investment platform. With support from development finance institutions in the US and Europe, AfricInvest has raised over US$100 million for health investment in Africa. It has funded at least 45 dialysis facilities in Africa, delivering over 130,000 dialysis sessions annually, primarily to remote and underserved communities all at affordable costs. A combination of these approaches at national, regional and continental level will accelerate Africa’s withdrawal from aid dependency. Professor Francisca Mutapi is a professor in global health infection and immunity at the University of Edinburgh, where she is also the deputy director of the TIBA (Tackling Infections to Benefit Africa) Partnership, and co-director of the Global Health Academy at the university.

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